The power of ECT

This really cool video comes courtesy of Grant Jensen et al. from their recent Review for Nature Reviews Microbiology. It shows an intact Bdellovibrio bacteriovorus cell imaged by ECT.

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At Nature Reviews Microbiology, I had the pleasure of handling a really interesting Review from Grant Jensen et at. that explores how recent advances in electron cryotomography (ECT) have provided structural and mechanistic insights into the physiology of bacteria and archaea.

The video above is part of that article, and I think it's so cool that I really wanted to share it with you guys. It shows "an intact Bdellovibrio bacteriovorus cell in standard media was plunge-frozen and imaged by ECT. The resulting tilt-series of images was reconstructed into a 3D tomogram. The movie shows the full reconstruction and segmentation, as well as fitting of crystal structures into EM densities."

I hope you enjoy it as much as I did!

Claudio Nunes-Alves

Senior Editor, Nature Microbiology

I'm a senior editor at Nature Microbiology, interested in all things bacteria, virus, archaea, fungi and parasites (but I mostly handled articles focusing on bacterial physiology, evolution, parasites and archaea). Before joining Nature, I studied biochemistry at the University of Porto, Portugal, as an undergrad; and was a grad student and post-doc in the labs of Margarida Correia-Neves (ICVS, Braga, Portugal), Sam Behar (Brigham and Women's Hospital and Harvard Medical School, Boston, MA, and then at UMass Medical School, Worcester, MA) and Christophe Benoist (at Harvard Medical School, Boston, MA), where I studied multiple aspects of immunity to tuberculosis.


Go to the profile of Andrew Jermy
over 5 years ago
Stunning video, thanks for sharing here Claudio!
Go to the profile of Matti Jalasvuori
over 5 years ago
Very nice science (and visualisation).