Ashraf Zarkan

Research Fellow, University of Cambridge
  • University of Cambridge
  • United Kingdom


Antimicrobials and resistance Bacteria Biofilms Infectious diseases Microbial genetics

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Inhibiting indole signalling offers a potential strategy for combatting antibiotic persisters

A lesser-known aspect of antibiotic resistance is the ability of bacterial persister cells to survive antibiotic treatment through dormancy. We find that indole signalling increases E. coli quinolone persisters, suggesting that indole inhibition may provide a method to enhance quinolone antibiotics


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