The 50 most downloaded Nature Communications articles* on SARS-CoV-2 published in 2020 illustrate the collaborative efforts of the international community to combat the ongoing pandemic. These papers highlight valuable research into the biology of coronavirus infection, its detection, treatment as well as into vaccine development and the epidemiology of the disease.

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^{* Data obtained from SN Insights (based on Digital Science's Dimensions) and has been normalised to account for articles published later in the year.}

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