April 2017 cover

Crystal structures define the molecular basis of antibody neutralization of RSV. Image by James Crowe and Jarrod Mousa; Cover Design: Samantha Whitham
April 2017 cover

Stopping RSV in its tracks

Crystal structures of two potent RSV antibodies in complex with the RSV fusion protein determine the molecular basis for neutralization of the virus, including a new antigenic site and the basis for cross-reactivity with human metapneumovirus.

Refers to "A novel pre-fusion conformation-specific neutralizing epitope on the respiratory syncytial virus fusion protein" by Mousa et al.


"Structural basis for antibody cross-neutralization of respiratory syncytial virus and human metapneumovirus" by Wen et al.

Nature Microbiology 2: 16271 (2017)

Nature Microbiology 2: 16272 (2017)

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