We analyzed the distribution of outer membrane (OM) attachment mechanisms across the whole tree of Bacteria, and we made a hypothesis on how gram-positives might have emerged. We tested it by perturbing OM tethering in the diderm Firmicute Veillonella. The results surprised us!
E. coli ST58 are supposed to be environmental commensals and yet they are a globally emerging cause of sepsis. What can genomic epidemiology reveal about their rise to prominence?
Understanding the transmission dynamics of SARS-CoV-2 amongst university students is critical to the implementation of effective mitigation strategies.